Start & Save

Savings on your prescription

If you and your healthcare provider have decided that Zembrace® SymTouch® or Tosymra® is right for you, support may be available to help with navigating out‑of‑pocket costs.*

Not an actual patient. For illustrative purposes only.

Not actual size.

Your prescription can be sent to most pharmacies, but BlinkRx is a digital pharmacy service. If your healthcare provider prescribes ZEMBRACE SYMTOUCH or TOSYMRA through BlinkRx and you are commercially insured and eligible, BlinkRx will work with your insurance to apply available savings to your prescription.

With BlinkRx, you can expect:

  • Lowest, eligible price based on your insurance
  • Digital payments
  • Dedicated pharmacist support
  • Free nationwide delivery and refill reminders
  • Eligible, commercially insured patients pay as little as $0 on each prescription*

If you have questions about using BlinkRx, call 1‑844‑926‑2480 or email support@blinkrx.com

*Valid only for those patients with commercial prescription insurance coverage who meet eligibility criteria. Offer not valid for (i) prescriptions paid, in whole or in part, by any federal, state, or government‑funded insurance programs (for example, Medicare, Medicare Advantage, Medigap, Medicaid, Veterans Affairs (VA), Department of Defense (DoD), or TRICARE), (ii) for cash‑paying patients, (iii) where product is not covered by patient’s commercial insurance, (iv) where patient’s commercial insurance plan reimburses them for the entire cost of their prescription drug, or (v) where prohibited by law or by the patient’s health insurance provider. If at any time a patient begins receiving prescription drug coverage under any federal, state, or government‑funded healthcare program, patient will no longer be able to use the savings program. Patients may not seek reimbursement for the value of the out‑of‑pocket expense covered by the Program from any third‑party payer, whether public or private. The Program is valid ONLY for qualifying patients residing in the 50 U.S. states or Puerto Rico with commercial insurance who have a valid prescription for an FDA‑approved indication for the qualifying Tonix Medicines therapy. The Program is not health insurance. This offer may not be combined with any other rebate, coupon or offer. Out‑of‑pocket assistance under the Program is not transferable. Tonix Medicines reserves the right to rescind, revoke, or amend the Program without notice. The patient/caregiver must certify their responsibility for complying with applicable limitations, if any, of any commercial insurance and reporting requirements regarding receipt of Program benefits, if necessary, to any commercial insurer. The Program is subject to termination or modification at any time.

INDICATION

What are ZEMBRACE® SymTouch® (sumatriptan succinate) injection and TOSYMRA® (sumatriptan) nasal spray?

ZEMBRACE SymTouch and TOSYMRA are prescription medicines used to treat acute migraine headaches with or without aura in adults who have been diagnosed with migraine. ZEMBRACE SymTouch and TOSYMRA are not used to prevent or decrease the number of migraine headaches you have or for the treatment of hemiplegic or basilar migraines. ZEMBRACE SymTouch and TOSYMRA are not indicated as treatments for cluster headache or for use in children under 18 years of age.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ZEMBRACE SymTouch and TOSYMRA?

ZEMBRACE SymTouch and TOSYMRA can cause serious side effects, including heart attack and other heart problems, which may lead to death. Stop use and get emergency help if you have any signs of a heart attack:

  • discomfort in the center of your chest that lasts for more than a few minutes or goes away and comes back
  • severe tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw
  • pain or discomfort in your arms, back, neck, jaw, or stomach
  • shortness of breath with or without chest discomfort
  • breaking out in a cold sweat
  • nausea or vomiting
  • feeling lightheaded

ZEMBRACE SymTouch and TOSYMRA are not for people with risk factors for heart disease (high blood pressure or cholesterol, smoking, overweight, diabetes, family history of heart disease) unless a heart exam shows no problem.

Do not use ZEMBRACE SymTouch or TOSYMRA if you have:

  • heart problems or a history of heart problems
  • narrowing of blood vessels to your legs, arms, stomach, or kidney (peripheral vascular disease)
  • uncontrolled high blood pressure
  • hemiplegic or basilar migraines. If you are not sure if you have these, ask your healthcare provider
  • had a stroke, transient ischemic attacks (TIAs), or problems with blood circulation
  • severe liver problems
  • an allergy to sumatriptan or any of the ingredients of ZEMBRACE SymTouch or TOSYMRA
  • taken any of the following medicines in the last 24 hours: almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, ergotamines, or dihydroergotamine. Ask your healthcare provider for a list of these medicines if you are not sure
  • are taking certain antidepressants, known as monoamine oxidase (MAO)-A inhibitors or it has been 2 weeks or less since you stopped taking a MAO-A inhibitor. Ask your healthcare provider for a list of these medicines if you are not sure

Before taking ZEMBRACE SymTouch or TOSYMRA, tell your healthcare provider about all your medical conditions, including if you:

  • have high blood pressure
  • have high cholesterol
  • have diabetes
  • smoke
  • are overweight
  • have heart problems or a family history of heart problems or stroke
  • have kidney problems
  • have liver problems
  • have had epilepsy or seizures
  • are not using effective birth control
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and supplements. Especially tell your healthcare provider if you take antidepressant medicines called: selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), or monoamine oxidase inhibitors (MAOIs).

ZEMBRACE SymTouch and TOSYMRA can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.

ZEMBRACE SymTouch and TOSYMRA may cause serious side effects including:

  • Raynaud's syndrome: changes in color or sensation in your fingers and toes
  • stomach and intestinal problems: symptoms include sudden or severe stomach pain, stomach pain after meals, weight loss, nausea or vomiting, constipation or diarrhea, bloody diarrhea, and fever
  • problems with blood circulation to your legs and feet: symptoms include cramping and pain in your legs or hips; a feeling of heaviness or tightness in your leg muscles; burning or aching pain in your feet or toes while resting; numbness, tingling, or weakness in your legs; cold feeling or color changes in one or both legs or feet
  • hives (itchy bumps): swelling of your tongue, mouth, or throat
  • medication overuse headaches from using migraine medicine for 10 or more days each month. If your headaches get worse, call your healthcare provider
  • serotonin syndrome: a rare but serious problem that can happen in people using ZEMBRACE SymTouch or TOSYMRA, especially when used with antidepressant medicines called SSRIs or SNRIs. Call your healthcare provider right away if you have mental changes such as seeing things that are not there (hallucinations), agitation, or coma; fast heartbeat; changes in blood pressure; high body temperature; tight muscles; or trouble walking
  • increased blood pressure: significant increases have been reported, including in people with no history of high blood pressure
  • seizures have happened in people who have never had seizures before

The most common side effects of ZEMBRACE SymTouch and TOSYMRA include pain and redness at injection site (ZEMBRACE SymTouch only), tingling or numbness, dizziness, warm/hot sensation, burning sensation, feeling of heaviness, pressure sensation, flushing, feeling of tightness, application site (nasal) reactions (TOSYMRA only), abnormal taste and throat irritation (TOSYMRA only).

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all the possible side effects of ZEMBRACE SymTouch and TOSYMRA. For more information, ask your healthcare provider.

This is the most important information to know about ZEMBRACE SymTouch and TOSYMRA, but it is not comprehensive. For more information, talk to your healthcare provider and read the Patient Information and Instructions for Use. You can also visit https://www.tonixpharma.com or call Tonix Medicines, Inc. at 1‑888‑869‑7633.

Please see additional safety information in the full Prescribing Information for ZEMBRACE SymTouch and TOSYMRA.

Call your healthcare provider for medical advice about side effects. You may report side effects to Tonix Medicines, Inc. at 1‑888‑869‑7633 or to the FDA at 1‑800‑FDA‑1088 or www.FDA.gov/medwatch.

MLT‑DTC‑260006 05/26

MLT‑DTC‑260005 05/26